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Stacks

Tesamorelin/Ipamorelin

Tesamorelin + Ipamorelin

Amino acid sequence

Combo display: tesamorelin scaffold · Ipamorelin Aib-His-D-2-Nal-D-Phe-Lys

  • Stack

Scientific Overview

Tesamorelin/Ipamorelin is a two-peptide research stack: tesamorelin, a growth hormone–releasing hormone analog, plus ipamorelin, a growth-hormone secretagogue. Component papers are published separately more often than as a fixed combination. This page does not claim a single pivotal trial of the pair.

Mechanism focus

Tesamorelin is studied at the GHRH receptor. Ipamorelin is studied at the ghrelin receptor. Overlapping research interest is GH-axis pharmacology, with each ligand documented on its own.

Research Use Cases

  • Combined GHRH-receptor and ghrelin-receptor models
  • Growth-hormone axis co-stimulation studies
  • Comparison with tesamorelin or ipamorelin alone
  • Identity testing of two-peptide preparations

Use-Case Study Notations

  • Case-study notation: tesamorelin reviews describe a GHRH analog with its own pharmacokinetic literature.
  • Case-study notation: ipamorelin is a selective GH secretagogue and a different receptor class.
  • Read the Tesamorelin and Ipamorelin pages for the single-compound identities.

Selected Studies

  1. 01 Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulationPubMed 25038357
  2. 02 Tesamorelin: a growth hormone-releasing factor analogue for HIV-associated lipodystrophyPubMed 22298602
  3. 03 Tesamorelin, a human growth hormone releasing factor analoguePubMed 19243281
  4. 04 Ipamorelin, the first selective growth hormone secretagoguePubMed 9849822
  5. 05 Efficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileusPubMed 19289567

Research Use Only. This page is educational and intended for laboratory research context. Products are not for human consumption and are not intended to diagnose, treat, cure, or prevent any disease.

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