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Cognitive

Selank

Tuftsin Analog Heptapeptide

Amino acid sequence

N-terminus →

01TThr
02KLys
03PPro
04RArg
05PPro
06GGly
07PPro
→ C
  • Polar
  • Hydrophobic
  • Acidic
  • Basic
  • Linear
  • 7 residues

Scientific Overview

Selank is a synthetic tuftsin analog investigated for anxiolytic-like and immunomodulatory properties in behavioral and molecular neuroscience research.

Mechanism focus

Tuftsin-family peptides intersect immune and CNS signaling; Selank studies examine gene-expression changes, stress-related behavior, and memory paradigms.

Research Use Cases

  • Anxiety and adaptive-behavior models
  • Alcohol/opioid withdrawal experimental paradigms
  • Functional connectomics with Semax comparators
  • Immunopeptide signaling research

Use-Case Study Notations

  • Case-study notation: rodent studies report attenuation of aversive morphine-withdrawal signs with Selank.
  • Case-study notation: ethanol-related memory impairment models have tested Selank for protective behavioral effects.
  • Keep claims tied to cited experimental systems; avoid clinical treatment language.

Selected Studies

  1. 01 Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in RatsPubMed 36322304
  2. 02 Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory ImpairmentPubMed 31625062
  3. 03 Selank and short peptides of the tuftsin family in the regulation of adaptive behaviorPubMed 14969422
  4. 04 Functional Connectomic Approach to Studying Selank and Semax EffectsPubMed 32342318
  5. 05 A new property of the synthetic anxiolytic Selank and its derivativesPubMed 15508574

Research Use Only. This page is educational and intended for laboratory research context. Products are not for human consumption and are not intended to diagnose, treat, cure, or prevent any disease.

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