Hormonal
Epithalon
Pineal Tetrapeptide
Amino acid sequence
N-terminus →
01AAla
02EGlu
03DAsp
04GGly
→ C
- Polar
- Hydrophobic
- Acidic
- Basic
- Linear
- 4 residues
Scientific Overview
Epithalon (also spelled epitalon) is a synthetic tetrapeptide based on a pineal peptide sequence. Cell and animal literature examines telomerase activity, telomere readouts, and pineal-peptide biology.
Mechanism focus
In vitro studies report telomerase-related effects and changes in telomere-length assays. The peptide is studied as a short pineal sequence, not as a growth-hormone secretagogue.
Research Use Cases
- Telomerase and telomere assays in cell models
- Pineal peptide research
- Comparative studies of short peptide sequences
- In vitro aging-model readouts
Use-Case Study Notations
- Case-study notation (in vitro): cell papers report telomere and telomerase readouts after epitalon exposure.
- Case-study notation: reviews describe epitalon as a pineal tetrapeptide with a still-developing evidence base.
- Clinical translation is limited. This page does not present outcome claims.
Selected Studies
- 01 Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising PropertiesPubMed 40141333
- 02 Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activityPubMed 40908429
- 03 Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitroPubMed 35413689
- 04 The Antioxidant Tetrapeptide Epitalon Enhances Delayed Wound Healing in an in Vitro Model of Diabetic RetinopathyPubMed 40493162
- 05 Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He micePubMed 16634527
Related compounds
Research Use Only. This page is educational and intended for laboratory research context. Products are not for human consumption and are not intended to diagnose, treat, cure, or prevent any disease.